Patrick Boaler

Personal

Patrick completed his PhD in 2022 at the University of Edinburgh under the supervision of Prof. Paul Lusby, and Prof. Guy Lloyd-Jones FRS. His thesis described the application of reaction monitoring and kinetic modelling techniques to supramolecular catalysis systems based on coordination capsules. Following this, Patrick gained postdoctoral experience in NMR methodology development with Prof. Dušan Uhrín, developing SHARPER pulse sequences for applications in reaction monitoring and complex mixture analysis. Patrick then re-joined the Lloyd-Jones group, working on a mechanistic study project funded by an industry partner before joining the Boron: Beyond the Reagent team in 2023.

Patrick takes a special interest in the modelling of complex chemical systems, and aims to develop and apply physical-organic chemistry techniques to study fundamental mechanisms involving boron. By combining reaction monitoring with simulating speciation and kinetics, his research will facilitate the prediction and control of the multifaceted reactivity exhibited in contemporary boron chemistry.
 

Publications

The Boroxine–Boronic Acid Equilibrium, Chen Li, Lia Sotorrios, Patrick J. Boaler, Valentas Olikauskas, Matteo Amico, Andrés García-Domínguez*, Andrew G. Leach*, and Guy C. Lloyd-Jones*, J. Am. Chem. Soc., 147, accepted, 2025

Kinetics of Sulfur-Transfer from Titanocene (Poly)Sulfides to Sulfenyl Chlorides: Rapid Metal-Assisted Concerted Substitution, Pedro H. Helou de Oliveira, Patrick J. Boaler, Guoxiong Hua, Nathan M. West, Robert T. Hembre, Jonathan M. Penney, Malik H. Al-Afyouni, J. Derek Woolins, Andrés García-Domínguez* and Guy C. Lloyd-Jones*, Chem. Sci., 15, 11875–11883, 2024 

The Origins of High-Activity Cage-Catalyzed Michael Addition, Patrick J. Boaler, Tomasz K. Piskorz, Laura E. Bickerton, Jianzhu Wang, Fernanda Duarte*, Guy. C. Lloyd-Jones* and Paul J. Lusby*, J. Am. Chem. Soc. 146, 19317–19326, 2024

Exogenous On and Off-cycle Cage Catalysis derived from Photo-Activating Host-Guest Encapsulation, Rebecca L. Spicer, Helen M. O’Connor, Yael Ben-Tal, Hang Zhou, Patrick J. Boaler, Fraser C. Milne, Euan K. Brechin,* Guy. C. Lloyd-Jones* and Paul J. Lusby*, Chem. Sci, 14, 14140–14145, 2023

SHARPER-DOSY: Sensitivity enhanced diffusion-ordered NMR spectroscopy, George Peat, Patrick J. Boaler, Claire L. Dickson, Guy C. Lloyd-Jones, and Dušan Uhrín*, Nat Commun, 14, 4410, 2023 

Mechanistic Analysis by NMR Spectroscopy: a Users Guide, Yael Ben-Tal, Patrick J. Boaler, Harvey J. A. Dale, Ruth E. Dooley, Nicole A. Fohn, Yuan Gao, Andrés García-Domínguez, Katie M. Grant, Andrew M. R. Hall, Hannah L. D. Hayes, Maciej M. Kucharski, Ran Wei, and Guy C. Lloyd-Jones*, Prog. Nucl. Magn. Reson. Spectrosc., 129, 28–106, 2022