Publications 2009-2005

A list of all the group's publications from 2009-2005.

2009

89. Hindered Ureas as Masked Isocyanates: Facile Carbamoylation of Nucleophiles under Neutral Conditions

M. Hutchby, C. E. Houlden, J. G. Ford, S. N. G. Tyler, M. R. Gagné, G. C. Lloyd-Jones* and K. I. Booker- Milburn*

Angew. Chem. Int. Ed., 48, 8721-8724, 2009.

Chosen by the editors as a Hot Paper.

Hindered Ureas as Masked Isocyanates: Facile Carbamoylation of Nucleophiles under Neutral Conditions

88. The Newman-Kwart Rearrangement of O-aryl thiocarbamates: Dramatic Reduction in Reaction Temperatures via Pd Catalysis

J. N. Harvey, J. Jover, G. C. Lloyd-Jones*, J. D. Moseley, P. Murray and J. S. Renny

Angew. Chem. Int. Ed., 48, 7612-7615, 2009.

Highlighted in Synfacts (2010) 1, 87-87.Chosen by the editors as a Hot Paper

The Newman-Kwart Rearrangement of O-aryl thiocarbamates: Dramatic Reduction in Reaction Temperatures via Pd Catalysis

87. A Structure-Based Rationale for selectivity in the Asymmetric Allylic Alkylation of Cyclohexenyl Esters Employing the Trost 'Standard Ligand' (TSL): Isolation, Analysis and Alkylation of the Monomeric Form of the Cationic η3-Cyclohexenyl Complex [(η3-c-C6H9)Pd(TSL)]+

Craig P. Butts, Emane Filali, Guy C. Lloyd-Jones*, Per-Ola Norrby*, David A. Sale and York Schramm

J. Am. Chem. Soc., 131, 9945-9957, 2009.

Highlighted in Chemical and Engineering News, 2009, vol. 87 (Issue 42), pp 31-33: 'A Tale of Two Catalysts'.

A Structure-Based Rationale for selectivity in the Asymmetric Allylic Alkylation of Cyclohexenyl

86. Cryptocatalytic 1,2-Alkene Migration in a σ-Alkyl Palladium Diene Complex

Louise A. Evans, Natalie Fey, Guy C. Lloyd-Jones*, M. Paz Muñoz, and Paul A. Slatford

Angew. Chem. Int. Ed., 48, 6262–6265, 2009.

Cryptocatalytic 1,2-Alkene Migration in a σ-Alkyl Palladium Diene Complex

85. Room Temperature Pd-catalyzed C—H Activation: ortho-Carbonylation of Aniline Derivatives

Chris E. Houlden, Marc Hutchby, Chris D. Bailey, J. Gair Ford, Simon N. G. Tyler, Michel R. Gagné, Guy C. Lloyd-Jones* and Kevin I. Booker- Milburn*

Angew. Chem. Int. Ed., 48, 1830–1833, 2009.

Chosen by the editors as a Hot Paper.

Room Temperature Pd-catalyzed C—H Activation: ortho-Carbonylation of Aniline Derivatives

84. Triflic Acid Mediated Dealkylative Lactonisation via NMR-Observable Alkyl Oxonium Intermediates

M. Paz Muñoz* and Guy C. Lloyd-Jones

Eur. J. Org. Chem., 516–524, 2009.

Triflic Acid Mediated Dealkylative Lactonisation via NMR-Observable Alkyl Oxonium Intermediates

83. Cleavage of tert-Butyl Benzoates with NaH in DMF. Comments on the Mechanism and a Simple and Safe Alternative Procedure

Emane Filali, Guy C. Lloyd-Jones* and David A. Sale

Synlett., 205–208, 2009.

Cleavage of tert-Butyl Benzoates with NaH in DMF. Comments on the Mechanism and a Simple and Safe Alternative Procedure

2008

82. Counterintuitive Kinetics in Tsuji-Trost Allylation: Ion-pair Partitioning and Implications for Asymmetric Catalysis

Louise A. Evans, Natalie Fey, Jeremy N. Harvey, David Hose, Guy C. Lloyd-Jones,* Paul Murray, A. Guy Orpen, Robert Osborne, Gareth J. J. Owen-Smith, and Mark Purdie

J. Am. Chem. Soc., 130, 14471–14473, 2008.

Highlighted in Synfacts, 3, 292-292, 2009.

Counterintuitive Kinetics in Tsuji-Trost Allylation: Ion-pair Partitioning and Implications for Asymmetric Catalysis

81. A New Class of 3′-Sulfonyl BINAPHOS Ligands: Modulation of Activity and Selectivity in Asymmetric Pd-Catalysed Hydrophosphorylation of Styrene

Katalin Barta, Giancarlo Francio, Walter Leitner,* Guy C. Lloyd-Jones,* and Ian Shepperson

Adv. Synth. Catal., 350, 2013–2023, 2008.

A New Class of 3′-Sulfonyl BINAPHOS Ligands: Modulation of Activity and Selectivity in Asymmetric Pd-Catalysed Hydrophosphorylation of Styrene

80. Distinct Reactivity of Pd(OTs)2: the Intermolecular Pd(II)-Catalyzed 1,2-Carboamination of Dienes

Christopher Houlden, Christopher Bailey, Gair Ford, Michel Gagné, Guy C Lloyd-Jones,* and Kevin I. Booker-Milburn*

J. Am. Chem. Soc., 130, 10066–10067, 2008.

Highlighted in Synfacts, 10, 1088-1088, 2008.

Distinct Reactivity of Pd(OTs)2: the Intermolecular Pd(II)-Catalyzed 1,2-Carboamination of Dienes

79. BINOL-3,3′-Triflone N-Methyl Phosphoramidites: Through-Space 19F,31P Spin-Spin Coupling with a Remarkable Dependency on Temperature and Solvent Internal Pressure

Matthias Kruck, M. Paz Muñoz, Hannah L. Bishop, Christopher G. Frost, Christopher J. Chapman, Gabriele Kociok-Köhn, Craig P. Butts* and Guy C. Lloyd-Jones*

Chem. Eur. J., 14, 7808–7812, 2008.

BINOL-3,3′-Triflone N-Methyl Phosphoramidites: Through-Space 19F,31P Spin-Spin Coupling with a Remarkable Dependency on Temperature and Solvent Internal Pressure

78. Decoupling Deprotonation from Metallation: thia-Fries rearrangement

Alan M. Dyke, Duncan M. Gill, Jeremy N. Harvey, Alison J. Hester, Guy C. Lloyd-Jones*, M. Paz Muñoz and Ian R. Shepperson

Angew. Chem. Int. Ed., 47, 5067–5070, 2008.

Decoupling Deprotonation from Metallation: thia-Fries rearrangement

77. Computational Descriptors for Chelating P,P- and P,N-Donor Ligands

Natalie Fey*, Jeremey N. Harvey*, Guy C. Lloyd-Jones, Paul Murray, A Guy Orpen*, Robert Osborne and Mark Purdie

Organometallics, 27, 1372-1383, 2008.

Computational Descriptors for Chelating P,P- and P,N-Donor Ligands

76. Mechanism and Application of the Newman-Kwart O→S rearrangement of O-Arylthiocarbamates

Guy C. Lloyd-Jones,* Jonathan D. Moseley and Joseph S. Renny

Synthesis, 2008, 661–689, 2008.

Mechanism and Application of the Newman-Kwart O→S rearrangement of O-Arylthiocarbamates

2007

75. Mechanism of Methyl-Esterification of Carboxylic Acids by Trimethylsilyl-diazomethane

Erik Kühnel, David D. P. Laffan, Guy C. Lloyd-Jones,* Teresa Martínez del Campo, Ian R. Shepperson and Jennifer L. Slaughter

Angew. Chem. Int. Ed., 46, 7075-7078, 2007

Mechanism of Methyl-Esterification of Carboxylic Acids by Trimethylsilyl-diazomethane

74. A Chemo- and Regio-Selective Three-Component Dihydropyrimidinone Synthesis

Chris D. Bailey, Chris E. Houlden, Grégory L. J. Bar, Guy C. Lloyd-Jones and Kevin I. Booker-Milburn*

Chem. Commun., 2932-2934, 2007

A Chemo- and Regio-Selective Three-Component Dihydropyrimidinone Synthesis

73. Isotopic Labelling in the Study of Organic and Organometallic Mechanism and Structure: An Account

Guy C. Lloyd-Jones* and M. Paz Muñoz

Invited contribution to the 50th Anniversary Special Issue of the Journal of Labelled Compounds and Radiopharmaceuticals, 50, 1072-1082, 2007

Isotopic Labelling in the Study of Organic and Organometallic Mechanism and Structure: An Account

72. Readily Accessible, Modular and Tuneable BINOL 3,3′-Perfluoroalkylsulfones: Highly Efficient Catalysts for Enantioselective In-Mediated Imine Allylation

Robert Kargbo, Yoko Takahashi, Santosh Bhor, Gregory R. Cook,* Guy C. Lloyd-Jones,* and Ian R. Shepperson

J. Am. Chem. Soc., 129, 3846-3847, 2007

Readily Accessible, Modular and Tuneable BINOL 3,3′-Perfluoroalkylsulfones: Highly Efficient Catalysts for Enantioselective In-Mediated Imine Allylation

71. Intermolecular Chirality Transfer from Silicon to Carbon: Interrogation of the Two- Silicon Cycle for Pd-Catalyzed Hydrosilylation by Stereoisotopochemical Cross-over

Sebastian Rendler, Martin Oestreich,* Craig P. Butts, and Guy C. Lloyd-Jones*

J. Am. Chem. Soc., 129, 502-503, 2007

Intermolecular Chirality Transfer from Silicon to Carbon

2006

70. Mechanism of Cycloisomerisation of 1,6-Heptadienes Catalysed by (tBuCN)2PdCl2: Remarkable Influence of Exogenous and Endogenous 1,6- and 1,5-Diene Ligands

Katharine L. Bray, Guy C. Lloyd-Jones,* M. Paz Muñoz, Paul A. Slatford, Emily H. P. Tan, Amanda R. Tyler-Mahon and Paul A. Worthington

Chem. Eur. J., 12, 8650–8663, 2007

Mechanism of Cycloisomerisation of 1,6-Heptadienes Catalysed by (tBuCN)2PdCl2: Remarkable Influence of Exogenous and Endogenous 1,6- and 1,5-Diene Ligands

69. Review: Organometallic Generation and Capture of ortho-Arynes

Alan M Dyke, Alison J. Hester and Guy C. Lloyd-Jones*

Synthesis, 4093-4112, 2006

Review: Organometallic Generation and Capture of ortho-Arynes

68. Highlight: The remarkable crossed co-isomerisation reaction of cyclopropyl ketones and enones via nickeladihydropyrans

Guy C. Lloyd-Jones

Angew. Chem. Int. Ed., 45, 6788-6790, 2006

Highlight: The remarkable crossed co-isomerisation reaction of cyclopropyl ketones and enones via nickeladihydropyrans

67. Mechanistic Implications of Pseudo Zero Order Kinetics in Kinetic Resolutions

Donna G. Blackmond,* Neil S. Hodnett and Guy C. Lloyd-Jones*

J. Am. Chem. Soc., 128, 7450-7451, 2006

Mechanistic Implications of Pseudo Zero Order Kinetics in Kinetic Resolutions

66. Enantioselective Homoallyl-cyclopropanation of Dibenzylideneacetone by Modified Allylindium Halide Reagents: Rapid Access to Enantioenriched 1-Styryl-Norcarene

Guy C. Lloyd-Jones*, Philip D. Wall, Jennifer L. Slaughter, Alexandra J. Parker and David P. Laffan

Prof. D. W. MacMillan Special Issue - Tetrahedron, invited submission, 62, 11402-11412, 2006

Enantioselective Homoallyl-cyclopropanation of Dibenzylideneacetone by Modified Allylindium Halide Reagents

65. Intermolecular Insertion of an N,N-Heterocyclic Carbene into a Nonacidic C-H bond: Kinetics, Mechanism and Catalysis by (K-HMDS)2

Roger W. Alder, Guy C. Lloyd-Jones* and Gareth J. J. Owen-Smith

Chem. Eur. J., 12, 5361-5375, 2006

Intermolecular Insertion of an N,N-Heterocyclic Carbene into a Nonacidic C-H bond

64. Asymmetric Allylic Substitution Catalyzed by C1-Symmetrical Complexes of Molybdenum: Structural Requirements of the Ligand and the Stereochemical Course of the Reaction

Andrei V. Malkov,* Laure Gouriou, Guy C. Lloyd-Jones,* Ivo Starý, Vratislav Langer, Paul Spoor, Victoria Vinader, and Pavel Kocovský*

Chem. Eur. J., 12, 6910–6929, 2006

Asymmetric Allylic Substitution Catalyzed by C1-Symmetrical Complexes of Molybdenum

63. On the Stability of the π-Allyl Intermediate in Molybdenum-Catalyzed Asymmetric Alkylations

Jennifer A. R. Luft, Zhi-Xiang Yu, David Hughes, Guy C. Lloyd-Jones, Shane W. Krska, K. N. Houk

Prof. J. Halpern Special Issue - Tetrahedron: Asymmetry, 17, 716-724, 2006

On the Stability of the π-Allyl Intermediate in Molybdenum-Catalyzed Asymmetric Alkylations

62. Catalysis by Organometallic Compounds

Guy C. Lloyd-Jones

Chapter in "The Investigation of Organic Reaction Mechanisms"

Edited by H. Maskill, Blackwell, Oxford, 2006

Catalysis by Organometallic Compounds

2005

61. Rate Enhancement by Ethylene in Ru-catalysed Ring-closing Metathesis of Enynes: Evidence for an "Ene-then-yne" Pathway that Diverts through a Second Catalytic Cycle

Guy C. Lloyd-Jones*, Robert G. Margue and Johannes G. de Vries

Angew. Chem. Int. Ed., 44, 7442–7447, 2005

Chosen by the referees as a Very Important Paper (VIP)

Rate Enhancement by Ethylene in Ru-catalysed Ring-closing Metathesis of Enynes

60. Pd(II) Catalysed Intermolecular 1,2-Diamination of Dienes

Grégory L. J. Bar, Guy C. Lloyd-Jones* and Kevin I. Booker-Milburn*

J. Am. Chem. Soc., 127, 7308-7309, 2005

Pd(II) Catalysed Intermolecular 1,2-Diamination of Dienes

59. Re-evaluation of the Mechanism of the Baylis-Hillman Reaction: Implications for Asymmetric Catalysis

Varinder K. Aggarwal*, Sarah Y. Fulford and Guy C. Lloyd-Jones*

Angew. Chem. Int. Ed., 44, 1706–1708, 2005

Re-evaluation of the Mechanism of the Baylis-Hillman Reaction: Implications for Asymmetric Catalysis

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